Hormesis is defined as any circumstance in which exposure of a cell or organism to a low dose of asubstance or condition results in an adaptive stimulatory/beneficial outcome, while exposure to a highdose results in an inhibitory / detrimental outcome. When plotted on a graph the shape of the doseresponse curve is biphasic, the hallmark of hormesis. This groundbreaking book "Hormesis: A Revolutionin Biology, Toxicology and Medicine" describes why and how hormesis is a fundamental feature of allliving systems and is based on the evolutionary principle of selection for genetic traits that conferthe ability to respond adaptively to adverse environmental conditions. Using numerous specific examplesthe authors explain why knowledge of hormesis is important for our health, our environment, and thefuture of our planet. Several chapters of the book describe emerging research findings that elucidatethe molecular and cellular underpinnings of the biphasic dose response/hormesis. The implications ofthe tapping of cellular systems that underlie hormesis for the discovery and optimization of new drugsand dietary formulations are described.
Paperback.:208 pages
Publisher.:Humana Press
Language..:English
Format....:PDF
Years.....:edition 2009
ISBN......:1607614944
Size......:2,5 mb
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